I've enjoyed watching the improvements to the boot speed, and I look forward to seeing what continual improvements come out of Meerkat as well, but...
I'm tired of the Mac's getting the long battery life out of their laptops. I'd like to see power saving as the next big area of improvement. I'm sure there's room for a 60% improvement with the right power management strategy, especially for netbooks and similar systems. Currently my Adamo according to powertop runs at about 1 watt at idle or at about 1.2 watts with me typing this message into the browser. It would be outstanding if the system was smart enough to autopower down bluetooth on it's own if no devices are currently in use. I'm sure there are plenty of optimizations that could be made, but I would expect to be able to go from about 3.5 hours on this system to somewhere in the range of 4.5 hours.
Compared to the 300% improvement we've seen in boot times over the last few releases, I don't think 60% battery life is out of the question for some systems. I definitely wouldn't put on hold anything like the UI improvements, or boot speed of course, but imagine a world where your computer is 30% more power efficient so the fans run less and the effect is a 45% reduction in power use for even high demand desktop systems.